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针刺治疗抑郁症残留症状失眠的随机对照临床研究

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目的 评价针刺治疗抑郁症残留症状失眠的临床疗效。方法 将2021 年6 月—2023 年12 月首都医科大学附属北京中医医院心身医学科门诊就诊的108 例抑郁症残留症状失眠患者采用区组随机法分为针刺组(8 周进行24 次针灸治疗)和药物组(服用艾司唑仑1 mg,每日1 次,连续8 周),每组54 例患者,观察基线和第4、8、12、20 周患者匹兹堡睡眠质量指数(PSQI)、失眠严重程度指数(ISI)、汉密尔顿抑郁量表(HAMD)评分、汉密尔顿焦虑量表(HAMA)评分、SF-36 健康调查问卷(SF-36)评分的变化,针刺治疗过程中采用针刺不良反应评价表评估针刺安全性。结果 与药物组比较,针刺组患者治疗后PSQI、ISI、HAMD评分、HAMA评分、SF-36 评分与基线的差值较高,差异均有统计学意义(P<0。05)。针刺组总有效率为 72。22%,药物组总有效率为 14。81%,两组间差异有统计学意义(P<0。05)。结论 针刺可以提升抑郁症残留症状失眠患者的睡眠质量,改善其抑郁焦虑情绪,提高患者的生活质量。
Acupuncture for residual sleep disturbances in patients remitted from major depressive disorder:a randomized controlled clinical research
Objective To observe the clinical effectiveness of the experience of famous traditional Chinese medicine doctors in the treatment of residual sleep disturbances in patients remitted from major depressive disorder.Methods The 108 patients remitted from major depressive disorder with residual sleep disturbances who were treated in the department of Psychosomatic Medicine,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University from June 2021 to December 2023,were randomly divided into acupuncture group(acupuncture treatments consisted of 24 sessions duration over 8 weeks)and medication group(patients take estazolam 1 mg daily for 8 weeks),54 cases in each.Assessments were carried out at baseline,4,8,12 and 20 weeks,including the Pittsburgh Sleep Quality Index(PSQI),Insomnia Severity Index(ISI),Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA),and SF-36.Results The difference in PSQI,ISI,HAMD,HAMA,and mental health scores(P<0.05)in the acupuncture group was greater than in the medication group.The total effective rate of the acupuncture and medication groups was 72.22%and 14.81%,respectively,and the difference was statistically significant(P<0.05).Conclusion Acupuncture can obviously improve sleep quality,alleviate symptoms of depression and anxiety,and improve quality of life in patients with major depressive disorder.

residual symptoms of major depressive disordersleeplessdepressioninsomniaacupunctureclinical research

付清楠、张捷、杨婧、李阳、满增琪、卢伟

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首都医科大学附属北京中医医院心身医学科 北京 100010

首都医科大学针灸推拿学院

抑郁症残留症状 失眠 郁病 不寐 针刺 临床研究

2024

北京中医药大学学报
北京中医药大学

北京中医药大学学报

CSTPCD北大核心
影响因子:1.568
ISSN:1006-2157
年,卷(期):2024.47(12)