包头医学院学报2014,Issue(5) :37-38,41.

老年恶性肿瘤患者外周血T淋巴细胞检测及意义

The Detection and Significance of T lymphocyte in the Peripheral Blood of Elderly Patients with Malignant Tumor

党连生 刘美玲 刘少旋
包头医学院学报2014,Issue(5) :37-38,41.

老年恶性肿瘤患者外周血T淋巴细胞检测及意义

The Detection and Significance of T lymphocyte in the Peripheral Blood of Elderly Patients with Malignant Tumor

党连生 1刘美玲 1刘少旋1
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作者信息

  • 1. 内蒙古包头医学院第一附属医院,内蒙古 包头 014010
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摘要

目的:了解老年恶性肿瘤患者的细胞免疫功能状况,为肿瘤的治疗及预防提供参考。方法:用流式细胞仪分别对肺癌、消化道肿瘤、乳腺癌患者及健康对照组外周血总 T 细胞、Th、Ts、Th/ Ts 细胞进行检测,用 SPSS 17.0软件对各组细胞的 Th 数值及 Th/ Ts 比值进行统计学分析。结果:Th 细胞数及 Th/ Ts 比值在肺癌、消化道肿瘤以及乳腺癌患者均明显低于正常对照组( P <0.05)。结论:老年恶性肿瘤患者的细胞免疫功能处于抑制状态。

Abstract

Objective:To analyze the status of cellular immune function in elderly patients with malignant tumors so as to provide a reference for tumor therapy. Methods:Flow cytometry was used to detect peripheral blood T(TT),Th,Ts and Th/ Ts cells,respectively,in patients with lung cancer,gastrointestinal cancer and breast cancer and healthy controls,with Th count and the ratio of Th/ Ts in each group analyzed by SPSS 17. 0. Results:The count of Th cells and the ratio of Th/ Ts in patients with lung cancer,gastrointestinal cancer and breast cancer were significantly lower than those in the control group( P < 0. 05). Conclusion:Cellular immune function in elderly patients with malignant tumors is in the state of suppression.

关键词

老年恶性肿瘤/T/细胞亚群/流式细胞仪

Key words

Malignant tumor/T - cell subsets/Flow cytometry

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出版年

2014
包头医学院学报
内蒙古科技大学包头医学院

包头医学院学报

影响因子:0.543
ISSN:1006-740X
被引量3
参考文献量3
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