Diagnostic value of serum HE4 and CA153 in ovarian cancer
Objective:To explore the diagnostic value of human epididymal protein 4(HE4)and carbohydrate anti-gen 153(CA153)in ovarian cancer by detecting their contents in normal healthy women and women with ovarian canc-er.Methods:A total of 81 healthy females and 81 females diagnosed with ovarian cancer were selected from Nanjing Maternity and Child Health Care Hospital from June 2020 to September 2021 for serum HE4 and CA153 detection.The detected results were statistically analyzed with SPSS software and the differences were compared.Results:The serum HE4 and CA153 in the ovarian cancer group were(47.94±24.62)pmol/L and(17.44±34.99)U/mL,and the ser-um HE4 and CA153 in the healthy women group were(41.86±8.21)pmol/L and(9.39±5.05)U/mL.The serum levels of HE4 and CA153 in women with ovarian cancer were higher than those in healthy women,and the differences were statistically significant.Conclusion:Serum HE4 and CA153 contribute to the diagnosis of ovarian cancer.
Ovarian cancerHuman epididymal protein 4Carbohydrate antigen 153