血清HE4和CA153在卵巢癌中的诊断价值
Diagnostic value of serum HE4 and CA153 in ovarian cancer
江望1
作者信息
- 1. 南京医科大学附属妇产医院(南京市妇幼保健院),江苏 南京 210000
- 折叠
摘要
目的:通过检测正常健康女性和卵巢癌女性的血清人附睾蛋白4(HE4)、糖蛋白抗原153(CA153)含量,发现其对卵巢癌的诊断价值.方法:选取 2020 年 6 月至 2021 年 9 月南京市妇幼保健院健康体检女性81 例和诊断为卵巢癌的女性81 例分别进行血清HE4、CA153 检测,将检测结果进行统计并比较差异.结果:卵巢癌组的血清HE4 为(47.94±24.62)pmol/L、血清CA153 为(17.44±34.99)U/mL,正常健康女性组的血清HE4 为(41.86±8.21)pmol/L、血清CA153 为(9.39±5.05)U/mL,卵巢癌组女性的血清HE4 和CA153 水平均高于健康女性组,且差异有统计学意义.结论:血清HE4 和CA153 有助于卵巢癌的诊断.
Abstract
Objective:To explore the diagnostic value of human epididymal protein 4(HE4)and carbohydrate anti-gen 153(CA153)in ovarian cancer by detecting their contents in normal healthy women and women with ovarian canc-er.Methods:A total of 81 healthy females and 81 females diagnosed with ovarian cancer were selected from Nanjing Maternity and Child Health Care Hospital from June 2020 to September 2021 for serum HE4 and CA153 detection.The detected results were statistically analyzed with SPSS software and the differences were compared.Results:The serum HE4 and CA153 in the ovarian cancer group were(47.94±24.62)pmol/L and(17.44±34.99)U/mL,and the ser-um HE4 and CA153 in the healthy women group were(41.86±8.21)pmol/L and(9.39±5.05)U/mL.The serum levels of HE4 and CA153 in women with ovarian cancer were higher than those in healthy women,and the differences were statistically significant.Conclusion:Serum HE4 and CA153 contribute to the diagnosis of ovarian cancer.
关键词
卵巢癌/人附睾蛋白4/糖蛋白抗原153Key words
Ovarian cancer/Human epididymal protein 4/Carbohydrate antigen 153引用本文复制引用
出版年
2024
NETL
NSTL
万方数据