The value of dual phase left atrial appendage CTA scanning in the diagnosis of left atrial appendage thrombus in patients with atrial fibrillation
Objective:To investigate the value of left atrial appendage CT angiography(CTA)double phase scan in the diagnosis of left atrial appendage thrombus in patients with atrial fibrillation.Methods:Thirty-six patients with atrial fibrillation were retrospectively collected from January 2020 to June 2022,and all patients underwent left atrial appendage(LAA)CTA double phase scan and transesophageal echocardiography(TEE).The sensitivity,specificity,positive predictive value,nega-tive predictive value and diagnostic compliance rate of LAA-CTA phase I and phase II diagnoses of LAA thrombus were calculated using the TEE test as the"gold standard",and the consistency of the LAA-CTA phase I and phase II diagnoses with the TTE diagnoses was evaluated using the Kappa test.Results:Twenty-one patients with left atrial appendage thrombus diagnosed in the first stage of LAA-CTA,15 patients with left atrial appendage thrombus diagnosed in the second stage,and 14 pa-tients with left atrial appendage thrombus diagnosed by TTE;the sensitivity,specificity,positive pre-dictive value,negative predictive value and diagnostic compliance rate of LAA-CTA phase I for the diagnosis of LAA thrombus were 64.29%,45.45%,42.86%,66.67%and 52.78%,respectively;the sensitivity,specificity,positive predictive value,negative predictive value and diagnostic compli-ance rate of LAA-CTA phase II for the diagnosis of LAA thrombus were 92.86%,90.91%,86.67%,95.24%and 91.67%,respectively,with statistically significant differences(P<0.05).The results of LAA-CTA phase I diagnosis of left atrial appendage thrombus were in general agreement with TEE diagnosis(Kappa =0.089),while the results of LAA-CTA phase II diagnosis of left atrial appendage thrombus were in better agreement with TEE diagnosis(Kappa =0.827),with statistically significant differences(P<0.05).Conclusion:The sensitivity,specificity,and diagnostic compli-ance rate of the second-stage scan are higher,and the results of the second-stage diagnosis of thrombus are in better agreement with TEE,so the left atrial appendage CTA double phase scan meth-od has higher clinical application value in the diagnosis of LAA thrombus.
Left atrial appendageCT angiographyDouble phase scanAtrial fibrillationThrombus