Prevalence and related factors of hyperuricemia in children and adolescents
Objective:To investigate the prevalence and related factors of hyperuricemia among children and adolescents in Baotou,Inner Mongolia.Methods:The data of children and adolescents aged 3-18 years from January 2021 to June 2022 were collected.The eligible children and adoles-cents were taken as the research objects,and the data were sorted out and the results were statistically analyzed.Results:The difference of SUA level between different genders and age groups was statisti-cally significant (P<0.05);the detection rates of HUA in boys aged 3-6,7-9 and 10-18 years old were 4.93%,3.21%and 4.41%,respectively.The detection rates of HUA in girls in the above age groups were 4.44%,3% and 2%,respectively.Among boys,there were significant differences in BUN,Cr,AST,Glu and blood lipid levels between HUA group and normal group (P<0.05),and among girls,there were significant differences in AST levels between HUA group and normal group (P<0.05).The results of correlation analysis showed that the SUA level in boys was positively correla-ted with BUN,Cr,ALT,TG and TC (P<0.05 ),while that in girls was negatively correlated with Glu (P<0.05),and positively correlated with BUN,Cr and ALT (P<0.05).The results of multi-variate logistic regression analysis showed that BUN and TC were the influencing factors of male HUA, and Glu was the influencing factor of female HUA.Conclusion:The serum uric acid level of children and adolescents in Baotou urban area is different in different ages and genders,and the detection rate of hyperuricemia in boys is higher than that in girls.Hyperuricemia can cause changes in BUN,Cr, AST,Glu and blood lipid levels;TC,BUN and Glu are the influencing factors of hyperuricemia in children and adolescents.