Correlation analysis between admission examination indexes and postoperative mortality in patients with osteoporotic vertebral compression fractures
Objective:To investigate the correlation between the indexes of laboratory examination and the mortality of patients with osteoporotic vertebral compression fracture (OVCF)after percutane-ous kyphoplasty (PKP).Methods:Patients who were diagnosed as OVCF and treated with PKP by the same surgical team in the Third Hospital of Baotou from June 2018 to June 2022 were selected.The blood routine,blood biochemical indexes and basic information of the patients at admission were col-lected,and the postoperative survival and Oswestry dysfunction index (ODI)questionnaire were fol-lowed up.According to whether the patients survived during the follow-up period,the patients were divided into survival group and death group.The related examination indexes of the two groups of pa-tients at admission were compared,and the influencing factors of the death outcome of the patients were analyzed.Results:The 1-year mortality rate of 176 patients with OVCF was 6.81％(12/176),and the total mortality rate was 18.75％(33/176)during the follow-up period.The AUC of bone mineral density (BMD)in predicting death was 0.797 (95％CI:0.699-0.895, P＜0.05),when the sensitivity was 66.7％and the specificity was 85.3％,the maximum diagnostic index was 0.520,and the diagnostic cut-off point was-3.430.The AUC of albumin (ALB)in pre-dicting death was 0.676 (95％CI:0.572-0.780,P＜0.05),when the sensitivity was 63.6％ and the specificity was 70.6％,the diagnostic index was 0.342,and the diagnostic cut-off point was 39.450 g/L.The AUC of neutrophil-to-lymphocyte ratio (NLR)in predicting death was 0.786 (95％CI:0.693-0.879,P ＜0.05 ),when the sensitivity was 81.8％ and the specificity was 65.0％,the diagnostic index was 0.468,and the diagnostic cut-off point was 3.120.The AUC of BMD,ALB and NLR combined to predict the death of patients was 0.871 (95％CI:0.798-0.945, P＜0.05).When the sensitivity was 75.8％and the specificity was 86.7％,the maximum diagnostic index was 0.625,and the diagnostic cut-off point was 4.945,which was higher than the area under the curve of NLR,BMD and ALB.Conclusion:The combination of BMD,ALB and NLR (combined index Y=0.528×NLR-3.526×BMD-0.227×ALB)can better predict the mortality of patients.
Bone mineral densityAlbuminNeutrophil-to-lymphocyte ratioOsteoporotic vertebral compression fracturesPercutaneous kyphoplastyMortality rate
万方数据
维普
