Etiological surveillance and analysis of hand-foot-mouth disease in Ulanqab City from 2020 to 2022
Objective:To analyze the etiological surveillance results of hand-foot-mouth disease in Ulanqab City from 2020 to 2022,and to provide basis for scientific prevention of hand-foot-mouth disease in Ulanqab city.Meth-ods:The samples of hand-foot-mouth cases collected by the Centers for Disease Control and Prevention of each coun-ty in Ulanqab City were collected.Real-time fluorescence quantitative PCR(RT-PCR)was used to detect the nucle-ic acid of enterovirus universal(EV),enterovirus 71(EV71)and coxsackie virus A16(CoxA16).Results:From 2020 to 2022,Ulanqab Centerfor Disease Control and Prevention received a total of 2058 throat swab samples of hand-foot-mouth disease cases,and 90 were generally positive for enterovirus,the positive rate was 4.37%,of which 41 were positive for Cox A16,with a positive rate of 1.99%,and 49 were positive for other types,with a positive rate of 2.38%.The positive rate of nucleic acid detection for hand-foot-mouth disease in different years and different regions was statistically significant(χ2=85.836,χ2=222.672,P＜0.05).Conclusion:From 2020 to 2022,hand-foot-mouth disease show a seasonal distribution in Ulanqab city;the positive rates of hand-foot-mouth disease are different in different regions and different age groups.Different years of hand-foot-mouth disease are dominated by other types of pathogens,suggesting that the region should pay attention to the detection of other enterovirus types,grasp the epi-demic etiology and variation,and provide a basis for scientific prevention and control of hand-foot-mouth disease.
Hand-foot-mouth diseaseEtiological surveillanceEnterovirusEnterovirus type 71Coxsackie vi-rus A16
万方数据
维普
