Correlation between intracranial atherosclerotic plaque shape and infract size
Objective:To evaluate the responsible vessels for ischemic stroke with computed tomography arteriography(CTA)and high resolution-magnetic resonance imaging(HR-MRI),and to explore the re-lationship between the occurrence and development of cerebral infarction and the degree of vascular stenosis,the composition and stability of the responsible plaque.Methods:Patients who underwent routine brain MRI examination from August 2018 to December 2020 in our hospital and diagnosed with acute cerebral infarction of unilateral middle cerebral artery(MCA)territory were included in the study.CTA and HR-MRI were used to analyze the degree of lumen stenosis caused by MCA atheromatous plaque and possible plaque compo-nents,20 cases in each group(CTA group and HR-MRI group)and the HR-MRI group included 10 pa-tients with HR-MRI plain scan(HR-MRI plain scan group,n=10)and 10 patients with contrast-en-hanced HR-MRI(HR-MRI contrast-enhanced group,n=10).The image post-processing workstation was used to outline the infarction and measure the maximum sectional area,and two experienced diagnosti-cians analyzed the stenosis degree,plaque composition,and plaque enhancement degree of the responsible vessels.Pearson's linear correlation and Spearman's rank correlation were used to evaluate the relationship between the degree of vascular stenosis and infarct size.Chi-square analysis was used to compare the infarct size of patients with different plaque components and different plaque enhancement degrees.Results:There was no correlation between the degree of responsible vessel stenosis and the infarct size in either the CTA group or the HR-MRI group(P>0.05).In the HR-MRI plain scan group,the plaques showed high or slightly high signal of T1WI,and the infarct size of those with the mixed signal of T2WI was significantly higher than that of those with other signals(P<0.05).In the HR-MRI contrast-enhanced group,the in-farct area of the patients with high plaque enhancement was significantly larger than that of the patients with moderate enhancement(P<0.05).Conclusion:Compared with the stenosis degree of the responsible ves-sel,intracranial arterial plaque hemorrhage and inflammatory response are more important prognostic factors for cerebral infarction.
万方数据
维普
