Study on the correlation between fetal neck transparent layer thickness and fetal prognosis in early pregnancy
Objective:To measure the thickness of fetal nuchal translucency(NT)by ultrasound in early pregnancy and explore the correlation between NT and fetal prognosis.Methods:A total of 2 779 pregnant women who underwent NT thickness measurement in early pregnancy from January 2017 to January 2019 were selected as subjects.According to the results of fetal NT thickness measurement,they were divided into NT thickening group(194 cases)and NT nor-mal group(2 585 cases).The relationship between different NT thickening amplitude groups and abnormal fetuses,and the relationship between different NT thickening amplitude groups and adverse pregnancy outcomes were analyzed.Re-sults:The incidence of adverse pregnancy outcomes in the NT thickening group was 30.93％,which was higher than 2.36％in the NT normal group,and the difference was statistically significant(P＜0.05).There was a significant difference in the incidence of adverse pregnancy outcomes between groups with different NT thickness(P＜0.05),and the incidence of adverse pregnancy outcomes increased with the increase of NT thickness.In the elderly pregnant women with NT thickening,the incidence of fetal adverse pregnancy outcomes among different age groups was statistically signif-icant(P＜0.05),and the ratio of fetal adverse pregnancy outcomes increased with the age of pregnant women.Conclu-sion:The thickening of transparent layer of fetal neck can increase the incidence of adverse pregnancy outcomes.Ultra-sound screening of fetal NT thickness in early pregnancy can improve the screening rate of fetal malformations,especially the detection rate of multiple structural malformations.When NT thickening is combined with advanced age,it will fur-ther improve the rate of predicting adverse pregnancy outcomes,which is worthy of clinical application.
Early pregnancyFetusFetal neck transparent layer thicknessPrognosisRelevance
万方数据
维普
