Treatment efficacy of intravenous injection of Reduning combined with Yupingfeng granules on viral myocarditis of pathogenic poison invading heart in Children
Treatment efficacy of intravenous injection of Reduning combined with Yupingfeng granules on viral myocarditis of pathogenic poison invading heart in Children
Objective To investigate the effect of intravenous Reduning injection and Yupingfen granules on children with vi-ral myocarditis(VMC)of pathogenic poison invading heart in Children and its influence on inflammatory factors and cardiac function indexes.Methods One hundred and forty-seven patients with pathogenic poison invading heart VMC were randomly di-vided into the control group(50 cases),the Reduning group(48 cases)and the combination group(49 cases).The clinical ef-ficacy,inflammatory factor changes and cardiac function indexes of the 3 groups were compared.Results After one week of treatment,the total effective rates of the Reduning group and the combination group were significantly better than that of the con-trol group;the levels of TNF,IL-6 and IFN-γ in the Reduning group and in the combination group were significantly lower than those in the control group(P＜0.01);the IFN-γ of the combined group was lower than that of the Reduning group;the indexes of CK-MB and BNP in the Reduning group and in the combination group were significantly lower than those in the control group,and the cTNI in the combination group was lower than those in the control group and the Reduning group(P＜0.01).After 2 weeks of treatment,the total effective rates of the Reduning group and the combination group were significantly higher than that of the control group,and the effective rate of the combination group was significantly higher than that of the Reduning group(P＜0.01);the levels of TNF and IFN-γ in the Reduning group and in the combination group were significantly lower than those of control group,and the levels of TNF and IFN-γ in the combination group were significantly lower than those of the Reduning group(P＜0.01);The indexes of CK-MB,cTNI and BNP in the Reduning group and in the combination group were significant-ly lower than those in the control group,while the indexes of CK-MB and cTNI in the combination group were significantly lower than those in the Reduning group(P＜0.01).Conclusion Venous Reduning injection combined with Yupingfeng granules can effectively improve the effective rate of pathogenic poison invading heart VMC and improve its prognosis,which may be related to effectively reducing the level of related inflammatory factors,reducing the level of myocardial injury markers,and repairing myo-cardial cells.
关键词
热毒宁注射液/玉屏风颗粒/病毒性心肌炎/临床研究
Key words
Reduning injection/Yupingfeng granule/viral myocarditis/clinical research
维普
万方数据