滨州医学院学报2024,Vol.47Issue(1) :44-47.DOI:10.19739/j.cnki.issn1001-9510.2024.01.009

温肺扶阳祛痰方治疗慢性阻塞性肺疾病稳定期的疗效

Clinical effect of Wenfei Fuyang Qutan Prescription on stable COPD

张金科
滨州医学院学报2024,Vol.47Issue(1) :44-47.DOI:10.19739/j.cnki.issn1001-9510.2024.01.009

温肺扶阳祛痰方治疗慢性阻塞性肺疾病稳定期的疗效

Clinical effect of Wenfei Fuyang Qutan Prescription on stable COPD

张金科1
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作者信息

  • 1. 天津市公安医院中医科 天津 300042
  • 折叠

摘要

目的 探讨温肺扶阳祛痰方治疗慢性阻塞性肺疾病(COPD)稳定期疗效.方法 选取COPD稳定期患者120例,随机分为两组.对照组应用噻托溴铵吸入粉雾剂+茶碱缓释片,研究组在此基础上应用温肺扶阳祛痰方,对两组的肺功能、免疫、炎症因子指标以及生活质量进行评估,确定其应用价值.结果 和对照组比较,研究组治疗后用力肺活量(FVC)、第1秒用力呼气容积(FEV1)、第1秒用力呼气容积/用力肺活量(FEV1/FVC)、6 min步行距离(6MWD)均增大(P<0.05),CAT评分降低(P<0.05).研究组治疗后C反应蛋白(CRP)、白细胞计数(WBC)、中性粒细胞计数(NEUT)水平均低于对照组(P<0.05).研究组治疗后CD4+、CD8+T细胞比例、IgA、IgG水平优于对照组(P<0.05).结论 COPD稳定期患者在常规西药治疗基础上应用温肺扶阳祛痰方治疗效果更佳,可以有效降低机体中的炎症因子水平,提高患者肺功能和免疫功能,值得推广应用.

Abstract

Objective To investigate the curative effect of Wenfei Fuyang Qutan Prescription in the treatment of chronic ob-structive pulmonary disease(COPD)in stable period.Methods One hundred and twenty patients with stable COPD were ran-domly divided into two groups.The control group was treated with tiotropium bromide inhaled powder aerosol+theophylline sus-tained-release tablets,while the study group was treated with Wenfei Fuyang Qutan Prescription besides the treatment of the con-trol group.The lung function,immunity,inflammatory factor indexes and quality of life of the two groups were evaluated to deter-mine its application value.Results After the treatment,compared with those in the control group,FVC,FEV1,FEV1/FVC,and 6MWD were higher in the study group,and CAT score was lower(P<0.05).The levels of CRP,WBC and NEUT in the study group were lower than those in the control group after the treatment(P<0.05).The levels of CD4+,CD8+,IgA and IgG in the study group were better than those in the control group after the treatment(P<0.05).Conclusion The treatment effect of Wenfei Fuyang Qutan Prescription in stable COPD patients on the basis of conventional western medicine is better,which can effectively reduce the level of inflammatory factors in the body and improve the lung function and immune function of patients,so it is worthy of popularization and application.

关键词

温肺扶阳祛痰方/慢性阻塞性肺疾病稳定期/免疫指标/炎症因子指标/生活质量/肺功能

Key words

Warming Lung Fuyang Expectorant Prescription/stable COPD/immune index/inflammatory factor index/quali-ty of life/lung function

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基金项目

天津市科技计划(2012KYSGAY023)

出版年

2024
滨州医学院学报
滨州医学院

滨州医学院学报

影响因子:0.548
ISSN:1001-9510
参考文献量21
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