摘要
目的:探讨早产儿贫血的相关影响因素.方法:选取410例早产儿为研究对象,按是否发生贫血分为贫血组(n=153)和非贫血组(n=257).比较两组早产儿一般资料(性别、胎数、受孕、分娩方式、胎膜早破、孕期贫血、母孕期胆汁淤积、妊娠期高血压、妊娠期糖尿病、妊娠期甲状腺功能减退、产前使用激素、宫内窘迫、心肺复苏、子痫前期、肺表面活性物质使用、机械通气使用、静脉营养使用、新生儿败血症、新生儿呼吸窘迫综合征、胎龄、出生体质量、住院时长、出生血红蛋白含量、出生红细胞计数、机械通气、怀孕、生产次数、孕母年龄等)资料,分析影响早产儿贫血的影响因素.结果:两组早产儿宫内窘迫、心肺复苏、子痫前期、新生儿败血症、新生儿呼吸窘迫综合征、机械通气、肺表面活性物质使用、静脉营养使用、住院时间、胎龄、机械通气时间、出生血红蛋白含量、出生体质量、出生红细胞计数比较,差异有统计学意义(P＜0.05);其他资料差异无统计学意义(P＞0.05).Logistic回归分析显示,住院日数、静脉营养使用、合并有孕母子痫前期是早产儿贫血的危险因素(OR=1.105,2.424,5.113,P＜0.05);出生体质量、出生血红蛋白含量是早产儿贫血的保护因素(OR=0.999,0.904,P＜0.05).结论:出生体质量轻、出生血红蛋白含量越低、住院时间长、孕母合并子痫前期、使用静脉营养会增加早产儿贫血发生的风险.
Abstract
Objective:To explore the related factors of anemia in premature infants.Methods:410 premature infants were retro-spectively collected and divided into anemia group(n=153)and non-anemia group(n=257)based on whether anemia occurs or not.The general information such as collect sex,number of fetuses,conception,mode of delivery,premature rupture of membranes,maternal anemia,maternal cholestasis,gestational hypertension,gestational diabetes,gestational hypothyroidism,prenatal use of hormones,intrau-terine distress,cardiopulmonary resuscitation,preeclampsia,pulmonary surfactant use,mechanical ventilation,intravenous nutrition,neo-natal septicemia,neonatal respiratory distress syndrome,gestational age,birth weight,length of stay,birth hemoglobin content,birth red blood cell count,mechanical ventilation,pregnancy,number of births,maternal age,multivariate,pregnancy,number of births,and mater-nal age were compared between two groups.Logistic regression analysis was used to screen the independent influencing factors.Results:There were statistically significant difference in intrauterine distress,cardiopulmonary resuscitation,preeclampsia,neonatal sepsis,neo-natal respiratory distress syndrome,mechanical ventilation,pulmonary surfactant use,intravenous nutrition use,length of hospital stay,gestational age,mechanical ventilation time,birth hemoglobin content,birth weight,and birth red blood cell count between two groups(P＜0.05).There was no statistically significant difference in other data(P＞0.05).The results of Logistic regression analysis showed that the number of days in hospital,the use of parenteral nutrition and preeclampsia were the risk factors of anemia in premature infants(OR=1.105,2.424,5.113,P＜0.05),birth weight and hemoglobin content were protective factors for anemia in premature infants(OR=0.999,0.904,P＜0.05).Conclusion:Lower birth weight,lower birth hemoglobin content,longer hospital stay,pregnant women with preeclampsia and use of intravenous nutrition will increase the risk of anemia in premature infants.
维普
万方数据