川北医学院学报2025，Vol.40Issue(1) ：81-84.DOI:10.3969/j.issn.1005-3697.2025.01.018

MRI弥散加权成像与动态增强扫描在前列腺癌诊断中的应用

Application of MRI diffusion weighted imaging and dynamic contrast-en-hanced MRI in diagnosing prostate cancer

颜显杰 王海 朱文淼
川北医学院学报2025，Vol.40Issue(1) ：81-84.DOI:10.3969/j.issn.1005-3697.2025.01.018
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  • 维普
  • 万方数据

MRI弥散加权成像与动态增强扫描在前列腺癌诊断中的应用

Application of MRI diffusion weighted imaging and dynamic contrast-en-hanced MRI in diagnosing prostate cancer

颜显杰 1王海 1朱文淼1
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作者信息

  • 1. 广州中医药大学梅州医院·梅州市中医医院·梅州市田家炳医院·梅州市中医药科学院医学影像科,广东梅州 514000
  • 折叠

摘要

目的:探讨磁共振(MRI)弥散加权成像(DWI)与动态增强扫描(DCE-MRI)在前列腺癌(PCA)诊断中的应用.方法:选取105例行MRI检查的疑似PCA患者为研究对象.患者均行DWI、DCE-MRI扫描检查,以病理活检为金标准,Kap-pa 一致性检验分析DWI、DCE-MRI单独扫描检查及两者联合检查诊断PCA的准确度、敏感度及特异度.结果:DWI检出PCA和前列腺良性病变分别66例、39例,DWI与病理活检诊断PCA的Kappa=0.918;DCE-MRI检出PCA和前列腺良性病变分别60例、45例,DCE-MRI与病理活检诊断PCA的Kappa=0.761;DWI诊断PCA的敏感度和准确度分别为95.59％、96.19％,高于 DCE-MRI 诊断 PCA 的敏感度和准确度(85.29％、88.57％)(x2=4.168、4.330,P=0.041、0.037);DWI+DCE-MRI 与病理活检诊断PCA的Kappa=0.937,且诊断PCA敏感度和准确度分别为98.53％、97.14％.结论:DWI较DCE-MRI诊断PCA准确度和敏感性更高,两者联合诊断可在一定程度提高前列腺癌诊断效能.

Abstract

Objective:To analyze the application of magnetic resonance imaging(MRI)diffusion weighted imaging(DWI)and dynamic contrast enhanced MRI(DCE-MRI)in the diagnosis of prostate cancer(PCA).Methods:105 patients with suspected PCA were selected as the research subjects,and they underwent DWI and DCE-MRI scanning.With pathological biopsy as the gold standard,Kappa consistency test was used to analyze the accuracy,sensitivity and specificity of DWI,DCE-MRI alone and their combined exami-nation in the diagnosis of PCA.Results:66 cases of PCA and 39 cases of benign prostatic lesions were detected by DWI respectively.The Kappa value of DWI and pathological biopsy in diagnosing PCA was 0.918.DCE-MRI detected 60 cases of PCA and 45 cases of benign prostatic lesions,and the Kappa value of PCA diagnosed by DCE-MRI and pathological biopsy was 0.761.The sensitivity and ac-curacy of DWI for PCA diagnosis were 95.59％and 96.19％,which were higher than 85.29％and 88.57％of DCE-MRI(x2=4.168,4.330,P=0.041,0.037).The Kappa value of DWI+DCE-MRI and pathological biopsy for PCA diagnosis was 0.937,and the sensitivity and accuracy were 98.53％and 97.14％,respectively.Conclusion:DWI has higher accuracy and sensitivity in the diagnosis of PCA than DCE-MRI,and the combined diagnosis of the two can up-regulate the diagnostic efficiency of prostate cancer to a certain extent.

关键词

磁共振弥散加权成像/动态增强扫描/前列腺癌/诊断

Key words

Magnetic resonance imaging diffusion weighted imaging/Dynamic contrast-enhanced MRI/Prostate cancer/Diagnosis

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出版年

2025
川北医学院学报
川北医学院

川北医学院学报

CSTPCD
影响因子：0.958
ISSN：1005-3697
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