The Lophatheri Herba leaf extract chewable tablets were developed with leaf extract powder of Lophatherum gracile Brongn.As the main raw material,and mannitol,lactose,citric acid,starch and magnesium stearate were added as auxiliary materials.The opti-mum condition of preparation process was selected by single factor investigation test and orthogonal design experimentation.The optimal prescription for Lophatheri Herba leaf extract chewable tablets was obtained:the leaf extract is 16%,the mass of mannitol vs lactose is 2∶1,magnesium stearate is 1.0%,citric acid is 2.0%.The chewable tablets have uniformly grayish yellow color,smooth and complete surface,suitable hardness and taste,which provides new thinkings for the further development and use of Lophatherum gracile leaves.This study is consistent with the current trend of functional,natural and diversified development for drug and dietary supplements.
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