成都大学学报(自然科学版)2024,Vol.43Issue(1) :26-33.DOI:10.3969/j.issn.1004-5422.2024.01.005

精加工聚丙交酯及聚己内酯基心血管支架研究进展

Research Progress on Finely Processed Poly lactic Acid and Polycaprolactone-Based Cardiovascular Stents

侯君孝 王羽 唐璐 董志红
成都大学学报(自然科学版)2024,Vol.43Issue(1) :26-33.DOI:10.3969/j.issn.1004-5422.2024.01.005

精加工聚丙交酯及聚己内酯基心血管支架研究进展

Research Progress on Finely Processed Poly lactic Acid and Polycaprolactone-Based Cardiovascular Stents

侯君孝 1王羽 1唐璐 2董志红1
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作者信息

  • 1. 成都大学机械工程学院,四川 成都 610106
  • 2. 成都大学附属医院,四川 成都 610081
  • 折叠

摘要

临床上治疗心血管疾病,通常在狭窄部位安置高分子可降解聚合物基血管支架,其主要作用是封堵破口及支撑血管真腔(3~12月),保持长期血管通透性.然而,术后并发症,如血管再狭窄阻碍了血管支架长期使用,并给患者带来高昂医疗费用.针对这一问题,介绍了血管支架的加工方法,以及聚丙交酯与聚己内酯基可降解聚合物支架材料研究进展与临床应用,并对聚合物材料在心血管支架中的应用研究进行了展望.

Abstract

The clinical treatment of this disease usually involves the placement of polymer-based biode-gradable vascular stents at the site of stenosis,whose main function is to seal the breach and support the true lumen of the vessel(3~12months)and to maintain long-term vascular permeability.However,post-operative complications,such as restenosis with haemocoagulation,prevent the long-term use of stents and result in high medical costs for patients.To address this problem,this paper describes the processing of vascular stents and the progress of research on polylactic acid and polycaprolactone-based biodegradable polymer stent materials and their clinical applications.Finally,this paper will provide an outlook on the research on the application of polymer materials in cardiovascular stents.

关键词

聚丙交酯/聚己内酯/精加工/心血管支架

Key words

polylactic acid/polycaprolactone/finishing/cardiovascular stents

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基金项目

四川省科技厅科技成果转化示范项目(23ZHSF0321)

国家级大学生创新创业训练计划创业实践与创业训练项目(2022110790015)

省级大学生创新创业训练计划创业实践与创业训练项目(S202311079008X)

出版年

2024
成都大学学报(自然科学版)
成都大学

成都大学学报(自然科学版)

影响因子:0.357
ISSN:1004-5422
参考文献量48
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