Effect of Phloroglucin on the Observation Effect of Esophagogastric Junction in Painless Gastroscopy and Its Safety Analysis
Objective To analyze the effect and safety of phloroglucinol on the observation of the esophagogastric junction during painless gastroscopy.Method A control group consisting of 135 cases underwent painless gastroscopy,and an observation group consisting of 115 cases(painless gastroscopy plus phloroglucinol) was randomly formed from patients who underwent painless gastroscopy between September 2022 and February 2023 based on the odd-evenness of their registration numbers.The esophagogastric junction observation effect,lesion detection rate,endoscopic features of lesions,pathological outcomes,and intraoperative and postoperative adverse responses of the two patient groups were noted and monitored.Result This portion of the observation group had a greater observation rate of the esophagogastric junction and a higher rate of lesion detection than the control group,and the difference was statistically significant (P=0.038,P=0.035).In comparison to the control group,the observation group had a greater detection rate of non-red lesions; this difference is statistically significant(P=0.003).Between the two groups,there was no statistically significant difference in the occurrence of adverse responses or pathological results (P>0.05).The difference was statistically significant (P=0.003).The incidence of adverse responses and abnormal outcomes did not change statistically significantly between the two groups (P>0.05).Conclusion The esophagogastric junction's observation impact can be enhanced by applying phloroglucinol before the painless gastroscopy,which will increase the likelihood of lesions being discovered.Finding easily overlooked non-red lesions is one of its specific uses.Additionally,it is more secure and has fewer adverse effects.