可穿戴离子检测及电促渗系统研究
Study on Ion Detection and Electroosmosis System for Wearable
王正 1孙莉 2李胜民 2邹迎曙 2杨忠 2王会如 2薛宁 1刘春秀1
作者信息
- 1. 中国科学院空天信息研究院传感器技术国家重点实验室,北京 100190;中国科学院大学电子电气与通信工程学院,北京 100049
- 2. 北京市医疗器械检验研究院,北京 100070
- 折叠
摘要
汗液作为一种非侵入性健康监测的资源,含有丰富的生理信息,可以进行实时无创监测.然而,人在久坐或者睡眠时无法获得足够的汗液进行采样分析,若要实现汗液成分的长期原位监测并不容易.基于以上两点问题,主要通过电化学传感器与可穿戴传感技术相结合,以非侵入的方式监测汗液中的 Na+,并开发测试了一套集成的可穿戴平台,用于实时采集和分析汗液中Na+的浓度.本系统Na+在浓度为 20 mmol/L～160 mmol/L 的测试范围内,灵敏度达到 61.6 mV/decade.除此之外,可以根据受试者自身出汗量情况来调节系统刺激出汗的相关参数,从而能够减小长期电促渗药物刺激对于受试者的影响.
Abstract
Sweat as a resource for non-invasive health monitoring,is abundant in physiological information and can be monitored non-inva-sively in real time.However,people cannot sweat enough for sampling and analysis when they are sedentary or sleeping,and it is not easy to achieve long-term in situ monitoring of sweat composition.To solve these two problems,monitoring Na+in sweat in a non-invasive man-ner is focused on by combining electrochemical sensors with wearable sensing technology.An integrated wearable platform is developed for real-time collection and analysis of Na+concentration in sweat.The sensitivity of the system is 61.6 mV/decade in the range of 20 mmol/L to 160 mmol/L.In addition,the parameters of the system related to the stimulation of sweat can be adjusted according to the sweat volume of the subject,which can reduce the side effect of long-term electro osmotic drug stimulation.
关键词
汗液检测/穿戴式设备/电化学传感器/电促渗Key words
sweat detection/wearable devices/electrochemical sensors/electro-promoted osmosis引用本文复制引用
基金项目
国家重点研发项目(2020YFC2004500)
国家重点研发项目(2021YFB3200600)
国家自然基金项目(62273321)
国家自然基金项目(62073307)
国家自然基金项目(62204243)
国家自然基金项目(61774157)
医学研究平台项目(2019-I2M-5-019)
中科院预研项目(8091A140106)
出版年
2024
国家科技期刊平台
NSTL
万方数据