Construction and application of aptasensor based on exosomes
The detection method of exosome-based aptasensor has many advantages,such as rapid,sensitive,high-throughput,non-invasive or minimally invasive,liquid biopsy and cost-effective analysis,and has become a research hotspot in recent years.Current research progress of aptamers in detection field of exosomes and targeted delivery of exosomes is reviewed.Firstly,exosomes,aptamers and aptasensors,as well as aptamer screening techniques commonly used in recent years are introduced.Secondly,the construction and principle of aptasensor based on exosomes,application of aptamers in the field of exosomes are described.Finally,problems and challenges of aptamers encounter in current application field of exosomes are proposed.
exosomesaptamersystematic evolution of ligands by exponential enrichment(SELEX)aptasensorapplication
NETL
NSTL
万方数据
维普
