MicroRNA(miRNA)is a class of small single-stranded non-coding RNA widely found in eukaryotic cells,which regulates gene expression in organism by inducing mRNA degradation or regulating protein levels.Studies show that abnormal miRNA expression is closely related to a variety of human diseases and can be used as an ideal biomarker for early diagnosis and disease screening.Therefore,achieving accurate miRNA detection is of great significance for clinical diagnosis and medical research.Research fruits of miRNA detection methods around both traditional detection methods and novel miRNA biosensors are summarized,and also the future development tendency is proposed.
维普
万方数据