Polydimethylsiloxane(PDMS)is widely used in microfluidic chip technology. PDMS elastomer punching is an important part of microfluidic chip fabricating. The quality of punching directly affects the inflow and outflow of sample and product collection. The quality of hole is influenced by many factors,such as the thickness of chip and the aperture of puncher. A standard hole should meet the following elements:controlled size,good roundness and no cracks. It is found that the hole quality will be improved by placing sacrificial layers above or below the target punching position. Four key factors affecting the punching quality are systematically studied,and a series of images of PDMS holes are obtained through orthogonal experiments. Then,images are post-processed using the MATLAB program. The influence of the sacrificial layer on the hole quality is analyzed,and the optimal punching process parameters are obtained. The results show that the quality of holes can be effectively improved by placing thickness of 2 mm of soft material on the upper and lower sacrifice layers close to the chip during punching.
关键词
牺牲层/正交实验/参数优化/微加工工艺
Key words
sacrificial layer/orthogonal experiment/parameter optimization/micromachining process
维普
万方数据