Correlation analysis of MRI features of breast and feasibility of breast conserving surgery
Objective:To investigate the preoperative MRI features and clinicopathological features associated with breast conserving surgery(BCS)failure and success.Materials and Methods:The data of patients who planned to undergo BCS and underwent preoperative MRI examination from March 2018 to May 2021 were retrospectively analyzed,and divided into failure group and success group according to whether convert to mastectomy.Image features collected included:size,right and left side,whether the mass was a mass,depth,amount of fibroglandular tissue,whether it was symmetrical,associated signs,background parenchymal enhancement(BPE),temporal intensity profile,T1 signal,and T2 signal.Clinicopathological features included patient age,human epidermal growth factor receptor 2(HER-2),estrogen receptor(ER),progesterone receptor(PR),proliferation-marker Ki-67,molecular subtype,and intraductal carcinoma or not.Univariate and multivariate logistic regression were used to analyze the imaging features and clinicopathological features between the two groups,and differences were considered statistically significant at P＜0.05.Results:The sample sizes of the BCS failure and success groups were 47 and 91 respectively.Univariate and multivariate logistic regression analysis showed that BPE was significantly different between the two groups.Using BPE minimal reinforcement as a reference,there was no statistical difference between it and BPE mild reinforcement[dominance ratio(OR)=0.317,95％confidence interval(CI):0.374-6.552,P=0.654]There was a statistical difference between it and moderate enhancement(OR=1.674,95％CI:1.392-26.420,P=0.022)and heavy enhancement of BPE(OR=1.569,95％CI:1.128-25.809,P=0.044).However,there was no significant difference in other clinicopathological and imaging features between failure group and success group.Conclusions:BPE has a certain correlation with the success of BCS,higher BPE levels suggest a greater likelihood of BCS failure,which may be used as an effective indicator for the feasibility analysis of preoperative MRI evaluation of BCS and the formulation of accurate surgical strategies.
万方数据
维普
