首页|正常椎间孔段颈神经磁共振弥散张量成像相关参数研究及纤维束重建

正常椎间孔段颈神经磁共振弥散张量成像相关参数研究及纤维束重建

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目的 探讨正常人颈椎间孔段颈神经根弥散张量成像(diffusion tensor imaging,DTI)各向异性分数(fractional anisotropy,FA)及表观弥散系数(apparent diffusion coefficient,ADC)特点;运用弥散张量纤维束示踪成像(diffusion tensor tractography,DTT)技术重建显示颈神经根神经纤维束,为临床诊断及治疗神经根型颈椎病提供参考依据.材料与方法 收集50名健康志愿者(男25名,女25名)行颈神经DTI.测量双侧C5至C7神经根椎间孔近中远段颈神经根FA值及ADC值,C5~C7不同节段神经根FA值及ADC值采用ANOVA单因素方差分析;C5~C7相同节段神经根左右侧FA值及ADC值,采用配对样本t检验;C5~C7相同节段神经根椎间孔近中远段FA值及ADC值,两两比较采用LSD法检验.同时对双侧C5~C7神经根进行神经纤维束重建.结果 C5~C7不同节段神经根椎间孔近中远段FA值及ADC值均无明显差异.C5~C7相同节段神经根椎间孔段相同层面左右两侧神经根FA值及ADC值无明显差异.C5~C7相同节段神经根三个不同层面神经根FA值及ADC值差异有统计学意义(P均<0.05).运用DTT技术可以连续完整地重建并显示出C5~C7椎间孔段颈神经根神经纤维束.结论 运用DTI及DTT技术可以定量评估颈椎间孔段颈神经根并直观地重建显示出颈椎间孔段颈神经根神经纤维束,可以为临床神经根型颈椎病的诊断提供椎间孔近中远段颈神经根定量参数及直观重建影像.
Study of diffusion tensor imaging parameters in foraminal cervical nerve of healthy volunteers and fiber bundle reconstruction
Objective:To observe the intervertebral foramen segments of cervical nerve roots by diffusion tensor tractography(DTT)and quantitatively analyze diffusion tensor imaging(DTI)parameters of healthy volunteers,to provide the reference for clinical diagnosis and treatment of cervical spondylotic radiculopathy.Materials and Methods:DTI and DTT of the cervical nerve roots were performed in fifty healthy volunteers(25 males and 25 females).Mean fractional anisotropy(FA)and ADC values of the cervical nerve roots(both sides of cervical nerve roots C5 to C7,proximal,middle and distal to the cervical foraminal zone)were obtained.Differences among various segments of cervical nerve roots were compared with ANOVA test;Differences between two sides of the cervical nerve roots at the same cervical segment were compared with paired samples t-test;Differences between the proximal,middle and distal nerve to the cervical foraminal zone at the same cervical segment were compared with the LSD test.Nerve fiber bundle reconstruction was performed on the both sides of cervical nerve roots C5 to C7.Results:There was no significant difference in FA and ADC values among the proximal,middle and distal nerve to the cervical foraminal zone in different segments of C5 to C7.There was no significant difference in FA and ADC values between the left and right sides of the nerve roots at the same cervical segment.The difference in FA and ADC values between the nerve roots at three different levels of the same segment of C5 to C7 was significant(P<0.05).The whole length of the cervical nerve roots C5 to C7 could be visualized clearly by using DTT.Conclusions:DTI and DTT can quantitatively evaluate the cervical nerve roots in the cervical foraminal segment and visually reconstruct the cervical nerve bundles,and can provide quantitative parameters and visual reconstruction images of cervical nerve roots in the proximal,middle and distal segments of the intervertebral foramina for the diagnosis of cervical spondylotic radiculopathy.

diffusion tensor imagingdiffusion tensor tractographyintervertebral foramencervical nerve rootsmagnetic resonance imaging

李丙萱、时寅、丁洪园、邹月芬

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南京医科大学第一附属医院放射科,南京 210029

弥散张量成像 弥散张量示踪成像 椎间孔 颈神经根 磁共振成像

2024

磁共振成像
中国医院协会 首都医科大学附属北京天坛医院

磁共振成像

CSTPCD北大核心
影响因子:1.38
ISSN:1674-8034
年,卷(期):2024.15(1)
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