Theoretical basis and MRI research progress of probiotics in the treatment of mental diseases
Gut microbiota(GM)acts on the brain through the brain-gut axis and plays an important role in the occurrence and development of mental diseases.Probiotics can have beneficial effects on the brain by maintaining GM homeostasis and intestinal barrier integrity,thus ameliorating the negative physiological effects caused by mental illness.MRI can be used to observe changes in the function and structure of the host brain when probiotics treat psychiatric disorders.This paper summarizes the recent research on the evaluation of probiotics in the treatment of mental disorders(depression,schizophrenia,autism spectrum disorder,obsessive compulsive disorder,anxiety disorder)by acting on brain-gut-microbiome axis based on MRI.It provides a new idea and objective brain imaging basis for the treatment of mental diseases.
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维普
