MRI research progress of brain structure and function in patients with cognitive dysfunction after aneurysmal subarachnoid hemorrhage
Aneurysmal subarachnoid hemorrhage(aSAH)is common in young people with high disability and mortality,and over half of the patients have cognitive dysfunction after surgery.Cognitive dysfunction after aSAH is manifested in a variety of areas:language,memory,visual perception,information processing,attention,and executive function.It seriously affects the quality of life of patients,and brings heavy spiritual and economic burden to patients,families and society.Early diagnosis and treatment can help patients recover function and improve quality of life.But its diagnosis requires assessment on a series of neurocognitive scales,which is time-consuming and subjective.MRI is non-invasive and non-radiative.Different cranial imaging techniques including 3D T1WI,diffusion tensor imaging and function MRI applied to patients,we can obtain changes of brain microstructure and function from different perspectives,which offer unique insight into early diagnosis,disease monitoring,prognosis assessment and pathological mechanism of postoperative cognitive dysfunction in aSAH patients.This study aims to explore the MRI parameters related to the early diagnosis of aSAH and the assessment of postoperative cognitive dysfunction by reviewing the research progress of brain structural and functional MRI neuroimaging in patients with cognitive dysfunction afeter aSAH,so as to be beneficial to early treatment and improve prognosis.
aneurysmal subarachnoid hemorrhagecognitive dysfunctionmagnetic resonance imagingbrain structurebrain function
万方数据
维普
