首页|MRI影像组学预测局部进展期直肠癌新辅助放化疗疗效的研究进展

MRI影像组学预测局部进展期直肠癌新辅助放化疗疗效的研究进展

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局部进展期直肠癌(locally advanced rectal cancer,LARC)患者术前行新辅助放化疗(neoadjuvant chemoradiotherapy,nCRT)已成为常规疗法,对于nCRT疗效的评估既往研究多集中于MRI图像肉眼观察、直肠镜及术后病理等,这些方法都存在各自的局限性,对nCRT疗效的评估不足以指导临床对LARC患者个性化治疗.近些年随着影像组学的深入研究,发现影像组学在nCRT疗效的预测方面展现出良好的前景.因此,本文就影像组学预测LARC患者nCRT疗效及存在的不足等方面进行综述,旨在寻找更准确预测nCRT疗效的新方法,为临床制订后续治疗方案提供依据.
Research progress of radiomics in predicting the efficacy of neoadjuvant chemoradiotherapy for locally advanced rectal cancer
Preoperative neoadjuvant chemoradiotherapy(nCRT)has become a standard treatment for patients with locally advanced rectal cancer(LARC).The evaluation of nCRT efficacy has traditionally relied on visual assessment of MRI images,colonoscopy,and postoperative pathology.However,these methods have their own limitations.The evaluation of the efficacy of nCRT is not enough to guide the clinical personalized treatment of patients with LARC.Recent in depth investigations into radiomics have revealed promising potential for predicting the effectiveness of nCRT.Consequently,this study will review the research status of radiomics in predicting the efficacy and shortcomings of nCRT in patients with LARC,aiming to find a new method to predict the efficacy of nCRT more accurately and provide a basis for clinical follow-up treatment.

locally advanced rectal cancerneoadjuvant chemoradiotherapyradiomicsmagnetic resonance imaging

梁程、安小霞、李瑞、曹亮、郭顺林

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兰州大学第一临床医学院,兰州 730000

兰州大学第一医院放射科,兰州 730000

局部进展期直肠癌 新辅助放化疗 影像组学 磁共振成像

2024

磁共振成像
中国医院协会 首都医科大学附属北京天坛医院

磁共振成像

CSTPCD北大核心
影响因子:1.38
ISSN:1674-8034
年,卷(期):2024.15(1)
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