脑震荡后综合征(postconcussional syndrome,PCS)是脑外伤后最常见的慢性后遗症.PCS的损伤机制涉及多种神经病理生理过程,目前尚不明确.越来越多的磁共振成像技术,例如,扩散张量成像(diffusion tensor imaging,DTI)、灌注加权成像(perfusion weighted imaging,PWI)、氢质子磁共振波谱成像(hydrogen proton magnetic resonance spectroscopy,1H-MRS)等被用于探究PCS从急性期到慢性期的神经病理生理变化与临床症状的关系.本文根据患者受伤的不同时期及其疾病进展进行纳入,对多种高级MRI手段在PCS中的应用进行综述,从不同角度了解其潜在神经病理机制,更好地服务于疾病的诊疗及预后.
Abstract
Post concussion syndrome(PCS)is the most common chronic sequelae after brain injury.At present,the mechanism of injury of PCS involves a variety of neuropathophysiological processes and is still unclear.More and more MRI techniques,such as diffusion tensor imaging(DTI),perfusion weighted imaging(PWI),hydrogen proton magnetic resonance spectroscopy(1H-MRS)have being used to explore the relationship between neuropathophysiological changes and clinical symptoms of PCS from acute to chronic phase.In this review,in order to gain a deeper understanding of their underlying neuropathological mechanisms from different perspectives,we using various MRI methods in PCS to serve the diagnosis,treatment,and prognosis of diseases by the different stages of patient injury and the severity of symptoms.
关键词
脑震荡后综合征/磁共振成像/结构磁共振成像/功能磁共振成像/多模态磁共振成像/病理生理学
Key words
post concussion syndrome/magnetic resonance imaging/structural magnetic resonance imaging/functional magnetic resonance imaging/multimodal magnetic resonance imaging/pathophysiology
维普
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