Application of magnetic resonance fat quantification technique in liver tumors
Accumulation of fat in body organs increases the risk of cancer in various diseases,including benign liver lesions.In recent years,fatty liver disease has been increasingly recognized as a risk factor for hepatocellular carcinoma,and hepatocellular carcinoma associated with metabolism-associated fatty liver disease has been a growing healthcare burden worldwide.The intratumoral and peritumoral fat content of liver tumors is valuable in the diagnosis,differentiation,grading,and prognosis of liver tumors.Liver transplantation has received increasing attention as one of the therapeutic means for liver tumors,and hepatic steatosis is closely related to preoperative evaluation and postoperative monitoring of liver transplantation.In addition,liver injury caused during tumor treatment is also directly related to liver fat content.Therefore,liver fat quantification is of great significance in developing liver tumors,diagnosis and treatment,and prognosis assessment.In this paper,we review the application of MRI fat quantification techniques,including magnetic resonance spectroscopy(MRS),chemical shift imaging(CSI),and multi-echo Dixon techniques(including IDEAL-IQ and mDixon-Quant)in liver tumors aim to provide more accurate quantitative liver fat imaging marker,to provide an objective and scientific basis for the selection of tumor treatment modalities and the assessment of efficacy,which can be used to help the clinical non-invasive diagnosis and therapeutic evaluation of liver tumors.