Prognostic value of myocardial signal intensity heterogeneity based on late gadolinium enhancement in cardiac magnetic resonance in patients with myocarditis
Objective:To evaluate the prognostic role of left ventricular(LV)entropy in patients with myocarditis.Materials and Methods:A total of 56 consecutive patients diagnosed with clinically suspected myocarditis between July 2015 and October 2023 were included in this retrospective study.Clinical indicators,conventional cardiac magnetic resonance(CMR)parameters and LV entropy were assessed.Patients were categorised into good prognosis(n=42)and poor prognosis groups(n=14)according to whether they experienced major adverse cardiovascular events(MACE).Prognostic efficacy of LV entropy was assessed by receiver operating characteristic(ROC)curves.Kaplan-meier(K-M)analysis was used for survival analysis,and Log-rank test was used for survival comparison.Results:During follow-up 14 patients(25.00%)experienced MACE,and LV entropy was significantly higher in patients who experienced MACE(P<0.001).ROC curve analysis indicated that the area under ROC curve(AUC)of the LV entropy was 0.871,the sensitivity was 78.5%and the specificity was 83.2%.K-M analysis suggested that the overall survival rate was lower in patients with LV entropy≥7.805 than in patients with LV entropy<7.805(P<0.001).Conclusions:LV entropy could help predict the occurrence of MACE in patients with myocarditis,and contribute to a better clinical evaluation of the prognosis of patients with myocarditis.
国家科技期刊平台
NSTL
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