首页|静息态功能磁共振成像在癫痫中的研究进展

静息态功能磁共振成像在癫痫中的研究进展

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  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
癫痫是一种慢性神经系统疾病,其分类广泛、机制复杂,具有反复发作和不可预测的特点,对患者的生活造成了一定的影响.深度了解其病理生理机制对疾病的治疗和提高患者生活质量十分重要,静息态功能磁共振成像(resting-state functional magnetic resonance imaging,rs-fMRI)现已成为探究癫痫脑功能改变的有效方法.目前基于rs-fMRI研究癫痫的数据分析方法主要有低频振幅(amplitude of low frequency fluctuation,ALFF)、局部一致性(regional homogeneity,ReHo)、功能连接(function connection,FC)和图论分析.本文将对rs-fMRI的各种分析方法在癫痫中的应用作一综述,为癫痫的病理生理机制及术前定位、治疗提供重要参考.
Research progress of resting state functional magnetic resonance imaging in epilepsy
Epilepsy is a chronic neurological disease,its classification is wide,the mechanism is complex,has the characteristics of repeated seizures and unpredictable,which has caused a certain impact on the life of patients.Therefore,it is necessary to understand the pathophysiological mechanisms for the treatment of epilepsy and the improvement of patients'quality of life.Resting-state functional magnetic resonance imaging(rs-MRI)has become an effective method to investigate the changes of brain function in epilepsy.At present,the data analysis methods for epilepsy research based on rs-fMRI mainly include amplitude of low frequency fluctuation(ALFF),regional homogeneity(ReHo),function connection(FC)and graph theory analysis.This article provides a review of the application of various rs-fMRI analysis methods in epilepsy,aiming to provide imaging indicators for the pathophysiological mechanism,preoperative and precise clinical treatment of epilepsy.

epilepsymagnetic resonance imagingresting-state functional magnetic resonance imagingamplitude of low frequency fluctuationregional homogeneityfunction connectiongraph theory

郭佳慧、吴琼、高阳、赵鹤、谢生辉、李波、王少彧、张华鹏、王桠楠

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内蒙古医科大学附属医院影像诊断科,呼和浩特 010030

西门子医疗系统有限公司,上海 201318

癫痫 磁共振成像 静息态功能磁共振成像 低频振幅 局部一致性 功能连接 图论

内蒙古医科大学面上项目

YKD2022MS047

2024

10.12015/issn.1674-8034.2024.03.034

磁共振成像
中国医院协会 首都医科大学附属北京天坛医院

磁共振成像

CSTPCD北大核心
影响因子：1.38
ISSN：1674-8034
年,卷(期)：2024.15(3)
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