Peritumor refers to the junction zone between tumor and healthy tissue,which reveal unique physical and immune characteristics and play an important role in the whole process of tumor development.Radiomics contains a series of computer related technologies.It can extract large amounts of high-dimensional quantitative features from multi-modality medical images,then excavate the correlations between these features and the diagnosis/prognosis of disease.So as to provide quantitative and objective support for disease detection and treatment.On the basis of reading domestic and foreign documents,this paper summarized the segmentation of peritumoral tissue,the application of peritumoral radiomics in diagnosis and differential diagnosis,staging and pathological classification,tumor genetics,efficacy and prognosis prediction of tumor,and microvascular invasion of liver cancer,prospected its future development.The aim of this paper is to provide some reference for the research of tumor microenvironment and precision diagnosis and treatment.