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多对比度定量磁共振成像在中枢神经系统中的应用

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多对比度定量MRI是当前热门的MRI技术之一,已在神经影像的研究中取得了较多进展,主要包括基于磁共振集成(magnetic resonance image compilation,MAGiC)序列、多参数(multiple parametric,MTP)集成序列及战略性获取的梯度回波(strategically acquired gradient echo,STAGE)序列等MRI技术.它们可以通过一次扫描获得多种对比度及定量图像,与常规单独序列MRI相比,扫描时间显著缩短;同时作为一种三维序列,MTP集成序列融合了当前多种先进的技术,保证了图像的高信噪比和高分辨率.本文就多对比度定量MRI技术的原理及其在中枢神经系统中的研究进展、优势及局限性进行综述,旨在为该技术感兴趣的学者提供参考,推动其进一步研究及在临床中的应用.
Application of multi-contrast quantitative MR imaging in central nervous system
Multi-contrast quantitative MRI is one of the most popular MRI techniques who have been made many advances in the research of neuroimaging,mainly including the imagings based on magnetic resonance image compilation(MAGiC)sequence,multiple parametric(MTP)synthetic sequence and strategically acquired gradient echo(STAGE)sequence,etc.They can obtain multiple contrast and quantitative images in a single scan,and the scanning time is significantly shorter than that of the conventional MRI.At the same time,as a three-dimensional sequence,MTP synthetic sequence integrates a variety of current advanced technologies to ensure high signal-to-noise ratio and high resolution of the images.This article reviews the principle and research progress in the central nervous system,advantages and limitations of multi-contrast quantitative MRI,aiming to provide reference for interested scholars and promote its further research and clinical application.

central nervous systemmagnetic resonance imagingmulti-contrast magnetic resonance imagingmagnetic resonance image compilation sequencemultiple parametric synthetic sequence

缪佳丽、万欣月、付君言、张军

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复旦大学附属华山医院放射科,上海 200040

中枢神经系统 磁共振成像 多对比度磁共振成像 磁共振集成序列 多参数集成序列

国家重点研发计划项目

2022YFF0708700

2024

磁共振成像
中国医院协会 首都医科大学附属北京天坛医院

磁共振成像

CSTPCD北大核心
影响因子:1.38
ISSN:1674-8034
年,卷(期):2024.15(4)
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