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磁共振成像技术评估早产儿小脑发育的研究进展

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早产儿是指胎龄小于37周的新生儿,尽管大多数早产儿未有明显脑结构损伤,但后期仍存在神经发育障碍风险较高的问题,具体机制尚不明确,可能是由于早产扰乱了正常脑发育进程所致.近年对早产儿脑发育研究主要集中于大脑,但小脑在协调运动、学习及认知功能方面具有重要功能,目前有关早产儿小脑发育的研究相对较少.MRI是一种可在活体状态下提供有关脑体积、功能和代谢等信息的成像技术,对早产儿小脑发育的研究具有重要意义.因此,本文就MRI技术在评估早产儿小脑发育中的研究进展予以综述,旨在寻找早产儿小脑发育的生物学标志物,为早产儿小脑发育的病理生理学机制提供影像学依据.
Research progress of magnetic resonance imaging in evaluating cerebellar development in preterm infants
Preterm infants are defined as newborns born at a gestational age of less than 37 weeks.Although most preterm infants do not have obvious brain structural damage,there is still a higher risk of neurodevelopmental disorders in the later stage.The specific mechanism is not clear,which may be caused by premature birth disrupting the normal brain development process.In recent years,studies on the brain development of preterm infants mainly focus on the cerebrum,the cerebellum also plays an important role in coordinating motor,learning and cognitive functions,but there are relatively few studies on the cerebellar development of preterm infants.MRI is an imaging technique that can provide information about brain volume,function and metabolism in vivo,and it is of great significance for the study of cerebellar development in preterm infants.Therefore,this article reviews the research progress of magnetic resonance imaging in evaluating cerebellar development in preterm infants,with the aim of finding the biomarkers of cerebellar development in preterm infants and providing imaging evidence for the pathophysiological mechanism of cerebellar development in preterm infants.

preterm infantsmagnetic resonance imagingcerebellumbrain developmentbrain structurebrain function

巩贺、任庆发、徐东昊、殷志杰、王静、徐璐梦、李祥林

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滨州医学院医学影像学院,烟台 264003

滨州医学院附属医院放射科,滨州 256600

早产儿 磁共振成像 小脑 脑发育 脑结构 脑功能

山东省重点研发计划

2018YFJH0501

2024

磁共振成像
中国医院协会 首都医科大学附属北京天坛医院

磁共振成像

CSTPCD北大核心
影响因子:1.38
ISSN:1674-8034
年,卷(期):2024.15(4)
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