增强T2 FLAIR序列在颅内肿瘤影像诊断中的研究进展
Research progress of contrast-enhanced T2 FLAIR in intracranial neoplasms imaging diagnosis
梁泓中 1郭睿 2肖运平3
作者信息
- 1. 广西中医药大学研究生院,南宁 530200;广西医科大学附属柳州市人民医院放射科,柳州 545006
- 2. 广西医科大学附属柳州市人民医院放射科,柳州 545006;柳州市分子影像重点实验室,柳州 545006
- 3. 广西医科大学附属柳州市人民医院放射科,柳州 545006;柳州市分子影像重点实验室,柳州 545006;广西临床疾病生物技术研究重点实验室,柳州 545006
- 折叠
摘要
在颅内肿瘤诊疗过程中,对比增强MRI扫描是常用的影像学评估手段.临床上颅脑MRI增强检查首选T1WI序列.长期以来,增强T2液体衰减反转恢复(fluid-attenuated inversion recovery,FLAIR)被认为是评估软脑膜疾病和脑转移瘤的辅助序列.近年来,不断有研究报道增强T2 FLAIR序列在血脑屏障、血软脑膜屏障、血脑脊液屏障、血眼屏障、血迷路屏障及淋巴系统损伤相关疾病的检出、鉴别诊断方面具有一定优势.增强T2 FLAIR序列尽管在颅内肿瘤影像诊断中展现出巨大的潜力,但目前尚未广泛应用于临床,原因包括:(1)增强T2 FLAIR适用的疾病谱尚未完全阐明,(2)增强T2 FLAIR的规范扫描参数尚未确定,(3)增加MRI检查时间等.本文针对增强T2 FLAIR序列的技术特点、正常影像表现以及在颅内肿瘤影像诊断中的应用现状、最新进展进行综述,为以后进一步科研、临床应用提供参考.
Abstract
Contrast-enhanced MRI is a radiological assessment tool commonly used in the diagnosis and treatment of intracranial neoplasms.T1WI sequence is clinically the first choice for contrast-enhanced brain MRI.For a long time,contrast-enhanced T2 fluid-attenuated inversion recovery(FLAIR)has been considered as an auxiliary sequence for assessing leptomeningeal diseases and brain metastases.In recent years,studies have continuously reported that contrast-enhanced T2 FLAIR has certain advantages in the detection and differential diagnosis of diseases related to blood-brain barrier,blood-leptomeningeal barrier,blood-cerebrospinal fluid barrier,blood-ocular barrier,blood-labyrinthine barrier and lymphatic system injuries.Although contrast-enhanced T2 FLAIR has demonstrated the tremendous potential in the imaging diagnosis of intracranial neoplasms,contrast-enhanced T2 FLAIR has not been widely used in clinical practice due to the reasons such as:(1)the spectrum of diseases suitable for contrast-enhanced T2 FLAIR has not been fully elucidated,(2)the standard scanning parameters for contrast-enhanced T2 FLAIR have not been determined,(3)it increases the MRI examination time.This article provides an overview of the technical characteristics,normal imaging manifestations,current application status,and latest progress of the contrast-enhanced T2 FLAIR sequence in intracranial neoplasms imaging diagnosis.Provide references for further scientific research and clinical applications in the future.
关键词
颅内肿瘤/磁共振成像/对比剂/液体衰减反转恢复Key words
intracranial neoplasm/magnetic resonance imaging/contrast agent/fluid-attenuated inversion recovery引用本文复制引用
基金项目
柳州市科技计划项目(2022CAC0208)
广西壮族自治区卫生健康委员会自筹经费课题(Z-B20221364)
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据