Research progress of contrast-enhanced T2 FLAIR in intracranial neoplasms imaging diagnosis
Contrast-enhanced MRI is a radiological assessment tool commonly used in the diagnosis and treatment of intracranial neoplasms.T1WI sequence is clinically the first choice for contrast-enhanced brain MRI.For a long time,contrast-enhanced T2 fluid-attenuated inversion recovery(FLAIR)has been considered as an auxiliary sequence for assessing leptomeningeal diseases and brain metastases.In recent years,studies have continuously reported that contrast-enhanced T2 FLAIR has certain advantages in the detection and differential diagnosis of diseases related to blood-brain barrier,blood-leptomeningeal barrier,blood-cerebrospinal fluid barrier,blood-ocular barrier,blood-labyrinthine barrier and lymphatic system injuries.Although contrast-enhanced T2 FLAIR has demonstrated the tremendous potential in the imaging diagnosis of intracranial neoplasms,contrast-enhanced T2 FLAIR has not been widely used in clinical practice due to the reasons such as:(1)the spectrum of diseases suitable for contrast-enhanced T2 FLAIR has not been fully elucidated,(2)the standard scanning parameters for contrast-enhanced T2 FLAIR have not been determined,(3)it increases the MRI examination time.This article provides an overview of the technical characteristics,normal imaging manifestations,current application status,and latest progress of the contrast-enhanced T2 FLAIR sequence in intracranial neoplasms imaging diagnosis.Provide references for further scientific research and clinical applications in the future.