Prenatal MRI of fetal hippocampal infolding angle change in middle and third trimester
Objective:Prenatal MRI was used to study the changes of the hippocampal infolding angle(HIA)of fetuses in the second and third trimester of pregnancy.Materials and Methods:The imaging data of normal fetuses in the second and third trimester of pregnancy undergoing prenatal MRI in the Second Hospital of Hebei Medical University from January 2018 to December 2021 were collected and were retrospectively analyzed.HIA in the coronal section of fetal brain MRI using the fast imaging employing steady state acquisition(FIESTA)sequence was measured,the normal range of HIA in fetuses in the second and third trimester of pregnancy was analyzed,to explore its correlation with gestational age changes and clinical application value.Results:A total of 139 cases of fetuses in the second and third trimester of pregnancy were included in the study,with a gestational age ranging from 20 to 38 weeks(mean 29.17±3.90 weeks),and a male-to-female ratio of 105∶34.The data was divided into 6 groups based on gestational age,and the confidence interval of fetal HIA was analyzed.With increasing gestational age,the HIA on both sides increased linearly(R2=0.803,0.836,both P<0.001),and the HIA on the right side was greater than that on the left side.However,no gender differences were found in the left and right sides(P=0.898).Conclusions:Prenatal MRI revealed that the changes of the HIA in fetuses in the second and third trimester of pregnancy follows a certain pattern,which can provide imaging diagnostic evidence for diseases related to hippocampal structural abnormalities either in utero or after birth.
国家科技期刊平台
NSTL
万方数据
