类淋巴系统(glymphatic system,GS)是大脑中废物清除的途径,其功能受损可以通过沿血管周围间隙扩散张量成像分析(diffusion tensor imaging analysis along the perivascular space,DTI-ALPS)进行评估.目前,DTI-ALPS作为一种非侵入性方法已被广泛用于评估神经系统疾病中的GS功能改变,它在评估神经系统疾病的病程进展、认知障碍及预测预后等方面发挥了举足轻重的作用.本文就GS、DTI-ALPS方法与应用优势及其在神经系统疾病中的应用进行综述,旨在为神经系统疾病的病程进展、预测影响预后因素以及临床治疗疗效方面提供一定的参考.
Advances in the application of DTI-ALPS in brain glymphoid system related neurological diseases
Impairment of the glymphoid system(GS),a pathway for waste removal in the brain,can be assessed by diffusion tensor imaging analysis along the perivascular space(DTI-ALPS).Currently,DTI-ALPS has been widely used as a non-invasive method to assess GS function in neurological diseases,and it plays a pivotal role in assessing disease progression,cognitive impairment,and predicting prognosis in neurological diseases.Therefore,this article provides an overview of the introduction of the GS,the advantages of the DTI-ALPS method and its application,and its use in neurological disorders.
glymphoid systemdiffusion tensor imaging analysis along the perivascular spacemagnetic resonance imagingnervous systemcognitive impairment