DTI-ALPS在脑类淋巴系统相关神经系统疾病中的应用进展
Advances in the application of DTI-ALPS in brain glymphoid system related neurological diseases
牛训玲 1王承炎 1刘华琼 1李承龙 2狄宁宁 1姜兴岳 1许昌1
作者信息
- 1. 滨州医学院附属医院放射科,滨州 256603
- 2. 滨州医学院附属医院神经外科,滨州 256603
- 折叠
摘要
类淋巴系统(glymphatic system,GS)是大脑中废物清除的途径,其功能受损可以通过沿血管周围间隙扩散张量成像分析(diffusion tensor imaging analysis along the perivascular space,DTI-ALPS)进行评估.目前,DTI-ALPS作为一种非侵入性方法已被广泛用于评估神经系统疾病中的GS功能改变,它在评估神经系统疾病的病程进展、认知障碍及预测预后等方面发挥了举足轻重的作用.本文就GS、DTI-ALPS方法与应用优势及其在神经系统疾病中的应用进行综述,旨在为神经系统疾病的病程进展、预测影响预后因素以及临床治疗疗效方面提供一定的参考.
Abstract
Impairment of the glymphoid system(GS),a pathway for waste removal in the brain,can be assessed by diffusion tensor imaging analysis along the perivascular space(DTI-ALPS).Currently,DTI-ALPS has been widely used as a non-invasive method to assess GS function in neurological diseases,and it plays a pivotal role in assessing disease progression,cognitive impairment,and predicting prognosis in neurological diseases.Therefore,this article provides an overview of the introduction of the GS,the advantages of the DTI-ALPS method and its application,and its use in neurological disorders.
关键词
类淋巴系统/沿血管周围间隙扩散张量成像分析/磁共振成像/神经系统/认知障碍Key words
glymphoid system/diffusion tensor imaging analysis along the perivascular space/magnetic resonance imaging/nervous system/cognitive impairment引用本文复制引用
基金项目
山东省自然科学基金(ZR2019BH025)
滨州医学院科研启动基金(BY2017KYQD13)
出版年
2024
国家科技期刊平台
NSTL
万方数据