A review on imaging in evaluating tumor regression grade after neoadjuvant theatment for locally advanced colorectal cancer
Colorectal cancer is one of the common malignancies of the digestive system,about 60%-70%of colorectal cancer patients have locally advanced rectal cancer(LARC)at the time of diagnosis,neoadjuvant therapy(NAT)is the standard treatment for patients with LARC,in recent years,with NAT showing good treatment response in LARC,NAT has also been initially used in locally advanced colorectal cancer,but not all patients with locally advanced colorectal cancer(LACRC)can benefit from NAT.Consequently,it is an urgent clinical problem to accurately evaluate the treatment response of NAT and screen the NAT dominant population before surgery.There is abundant evidence that imaging can be used to assess the response of LACRC-NAT preoperatively.Therefore,this article reviews the application status,advantages and limitations of computed tomography,MRI,positron emission tomography/computed tomography,radiomics and deep learning in the evaluation of the response of LACRC-NAT,aiming to improve the accuracy of imaging evaluation of the response of LACRC-NAT and provide a comprehensive and objective imaging basis for the clinical formulation of individualized NAT protocols.
国家科技期刊平台
NSTL
万方数据
