首页|影像组学在常见妇科恶性肿瘤的研究进展

影像组学在常见妇科恶性肿瘤的研究进展

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宫颈癌(cervical cancer,CC)、卵巢癌(ovarian cancer,OC)和子宫内膜癌(endometrial cancer,EC)为妇科常见的三大恶性肿瘤,其发病率和死亡率较高并且逐年增长,及早明确诊断和治疗对改善其生存至关重要.目前,妇科恶性肿瘤的诊断方式主要为影像学和病理检查,但敏感性、准确性和特异性有限.新兴的影像组学技术通过将视觉影像信息转化为深层次的特征来进行量化研究,定量地评估病变,有利于提高病情评价的精准性.近年来,越来越多的研究发现基于计算机体层成像(computed tomography,CT)、MRI、正电子发射计算机体层成像(positron emission tomography/computed tomography,PET/CT)的影像组学能够无创精准地对常见妇科恶性肿瘤患者进行治疗前预评估,进而指导临床决策.本文将从影像组学的基本概述、工作流程及其在常见妇科恶性肿瘤的诊断、鉴别诊断、病理分型、组织学分级、淋巴结转移(lymph node metastasis,LNM)、淋巴血管间隙浸润(lymphovascular space invasion,LVSI)、分子表达、疗效及预后预测等方面的研究进展进行综述,并对未来研究方向进行展望,以期为优化医疗决策、推动精准医学的发展提供新思路.
Research progress of radiomics in common gynecologic malignancies
Cervical cancer(CC),ovarian cancer(OC)and endometrial cancer(EC)are the three most common gynecologic malignancies,with high morbidity and mortality and increasing year by year.Early diagnosis and treatment are essential to improve survival.At present,the main diagnostic methods of gynecologic malignancies are imaging and pathological examination,but their sensitivity,accuracy and specificity are limited.The emerging radiomics technology transforms visual image information into deep features for quantitative research and quantitative assessment of lesions,which is conducive to improving the accuracy of disease evaluation.In recent years,more and more studies have found that radiomics based on computed tomography(CT),MRI and positron emission tomography/computed tomography(PET/CT)can perform pre-treatment assessment of patients with gynecologic malignancies non-invasively and accurately,and may guide clinical decision-making.In this paper,the basic concept and workflow of radiomics and its research progress in the diagnosis,differential diagnosis,pathological type,histological grade,lymph node metastasis(LNM),lymphovascular space invasion(LVSI),molecular expression,efficacy and prognosis prediction of common gynecologic malignancies were reviewed,and make a prospect for future research,in order to provide new ideas for optimizing medical decision-making and promoting the development of precision medicine.

cervical cancerovarian cancerendometrial cancerradiomicsmagnetic resonance imaging

甘玲、华丽、陈绍俊

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广西医科大学,南宁 530000

广西医科大学第四附属医院/柳州市工人医院肿瘤科,柳州 545005

宫颈癌 卵巢癌 子宫内膜癌 影像组学 磁共振成像

广西壮族自治区重点研发计划

2021AB12004

2024

磁共振成像
中国医院协会 首都医科大学附属北京天坛医院

磁共振成像

CSTPCD北大核心
影响因子:1.38
ISSN:1674-8034
年,卷(期):2024.15(5)
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