多发性硬化合并抑郁症的多模态MRI技术研究进展
Research progress of multimodal MRI technology in multiple sclerosis complicated with depression
齐凯 1李昊 1徐君海 2任瑞 3李祥林1
作者信息
- 1. 滨州医学院医学影像学院,烟台 264003
- 2. 天津大学智能与计算学部,天津300350
- 3. 滨州医学院附属医院放射科,滨州 256600
- 折叠
摘要
抑郁症是多发性硬化症患者最常见的精神障碍之一,严重影响患者的生活质量和治疗预后.多发性硬化症受多种发病因素的影响,神经炎症、氧化应激、神经退行性改变是其常见的发病机制.随着神经影像学的进展,结构磁共振成像、功能磁共振成像被广泛应用于精神障碍疾病的研究中.本文综述了多模态MRI技术在多发性硬化合并抑郁症的研究新进展,为揭示多发性硬化合并抑郁症的病理生理机制提供了客观的影像学依据.
Abstract
Depression is one of the most common mental disorders in patients with multiple sclerosis, which seriously affects the quality of life and prognosis of patients. Influenced by many pathogenic factors, its pathophysiological mechanism is not clear. With the development of neuroimaging, structural MRI and functional MRI are widely used in the study of mental disorders. This review describes the imaging research progress of multimodal MRI in multiple sclerosis with depression, and provides objective imaging evidence for the pathophysiological mechanism of multiple sclerosis with depression.
关键词
多发性硬化症/抑郁症/磁共振成像/脑结构/脑功能Key words
multiple sclerosis/depression/magnetic resonance imaging/brain structure/brain function引用本文复制引用
基金项目
国家自然科学基金项目(62176181)
山东省自然科学基金项目(ZR2022MH118)
出版年
2024
国家科技期刊平台
NSTL
万方数据