首页|磁共振成像在颅内肿瘤周围脑区中的研究进展

磁共振成像在颅内肿瘤周围脑区中的研究进展

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肿瘤并不是单一生长的组织,其周围特异性的肿瘤微环境与其发展息息相关,肿瘤周围脑区是指肿瘤原发病灶周围邻近的大脑区域,在放射学上通常包括瘤周脑实质及瘤周水肿区域.充分认识并挖掘肿瘤及瘤周脑区的潜在放射学信息,将在肿瘤的科学研究及临床诊疗中获益.本文阐明了瘤周脑区的定义与形成机制,并对基于磁共振成像的各项技术,包括扩散成像、灌注成像、磁共振波谱成像、酰胺质子转移加权成像及影像组学,在颅内肿瘤周围脑区中的应用进展进行综述,旨在通过开展瘤周脑区的影像学研究继而为颅内肿瘤的鉴别诊断、基因分子分型、探寻术中切除范围、预测预后及监测疗效等方面提供新思路.
Progress in MRI in peritumoral brain zone of brain tumors
Tumors are not single-growing tissues, and the specific tumor microenvironment surrounding them is closely related to their development. Peritumor brain area refers to the adjacent brain area around the primary tumor lesion, and radiologically it usually includes peritumor brain parenchyma and peritumor edema area. Fully understanding and mining the potential radiological information of tumor and peritumoral brain area will benefit the scientific research and clinical diagnosis and treatment of tumor. In this article, we elucidate the definition and formation mechanism of the peritumor brain zone, and review the progress of magnetic resonance imaging-based techniques, including diffusion imaging, perfusion imaging, magnetic resonance spectroscopy, amide proton transfer-weighted imaging, and radiomics, in the application of the peritumor brain zone to intracranial tumors. The aim of this review is to provide new ideas for differential diagnosis, genomolecular typing, exploration of intraoperative resection range, prognosis prediction and monitoring of therapeutic efficacy of intracranial tumors.

brain tumorperitumor brain zonemagnetic resonance imagingimaging omicsmultimodality

赵恩东、施禹彤、宋雪琳、娄诗云、杨超

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大连医科大学附属第一医院放射科,大连 116000

大连大学附属新华医院神经内科,大连 116000

大连医科大学附属第二医院放射科,大连 116000

脑肿瘤 瘤周脑区 磁共振成像 影像组学 多模态

国家自然科学基金项目

81771663

2024

磁共振成像
中国医院协会 首都医科大学附属北京天坛医院

磁共振成像

CSTPCD北大核心
影响因子:1.38
ISSN:1674-8034
年,卷(期):2024.15(6)
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