Research progress of MRI radiomics in the efficacy evaluation and prognosis of neoadjuvant therapy for breast cancer
The incidence of breast cancer has jumped to the top of the global neoplastic lesions,and the incidence is still on the rise. Neoadjuvant therapy (NAT) has been widely used as the first-line treatment for patients with locally advanced breast cancer. Magnetic resonance imaging (MRI), with its good soft tissue and spatial resolution, is increasingly important in assessing lesion extent, early diagnosis, efficacy prediction, and prognostic assessment. MRI-based radiomics can analyze internal texture features that cannot be distinguished by the naked eye, which has great advantages in assessing tumor heterogeneity. Studies have demonstrated the advantages and disadvantages of MRI assessment at different time points of the NAT course in breast cancer, with multi-temporal assessment being more advantageous than single-temporal. The aim of this review is to investigate the current research status, controversies and application prospects of longitudinal temporal MRI images for evaluating neoadjuvant efficacy with the support of imaging histology, as well as the unique advantages of MRI imaging histology for predicting the long-term prognosis of neoadjuvant therapy in breast cancer patients. This study suggests the superiority of the multiseries longitudinal imaging histology model to evaluate tumor response, and provides ideas for more analysis methods of imaging histology in the future.