Research progress of CT and MRI with radiomics to predict microsatellite instability in colorectal cancer
Colorectal cancer is a common malignant tumor of the digestive tract with high mortality, and its pathogenesis is closely related to the genetic changes of tumor cells. Microsatellite instability (MSI) is a common genetic change that causes colorectal development and plays a crucial role in the development and progression of tumors and in the treatment and prognosis of patients. In recent years, medical imaging methods with the advantages of non-invasiveness and individualization have begun to make initial progress in evaluating high MSI (MSI-H) status in colorectal cancer. With the continuous optimization of software technology and the rise of artificial intelligence, computed tomography (CT) and MRI with radiomics methods have become increasingly important in the preoperative prediction, treatment, efficacy monitoring, and prognosis assessment of MSI-H status in colorectal cancer. This review aims to summarize the advantages and prospects of CT and MRI techniques and radiomics methods in predicting the MSI-H status of colorectal cancer, to provide more accurate and non-invasive MSI prediction methods for clinical practice, and provide new ideas for the selection of treatment measures for colorectal cancer patients.