超高场磁共振(ultra-high-field magnetic resonance,UHF-MR)对疾病诊断和细微结构显示一直是临床研究热点.但由于其固有特性,7 T UHF-MR的研究目前主要集中在中枢神经及部分骨肌系统疾病中.而5 T UHF-MR的问世,似乎为骨肌及全身系统的超高场成像带来了新的可能性.本文重点对UHF-MR的固有物理特性对骨肌系统疾病诊断的影响及UHF-MR在骨肌系统疾病中的临床研究进展展开综述,旨在增强医师对UHF-MR的了解,拓宽研究者的思路,进一步推动新型对比剂的开发、多模态成像技术的应用以及人工智能辅助诊断的结合,促进UHF-MR在骨肌系统疾病中的临床转化及应用.
Research Progress of ultra-high-field magnetic resonance imaging in musculoskeletal system
Ultra-high-field MR (UHF-MR) has been a hot spot in clinical research for disease diagnosis and fine structure display. However, due to its inherent characteristics, the research of 7 T UHF-MR is mainly focused on the central nervous system and some musculoskeletal diseases. The advent of 5 T UHF-MR seems to bring new possibilities for ultra-high-field imaging of musculoskeletal and systemic systems. This paper focuses on reviewing the impact of the inherent physical properties of UHF-MR on the diagnosis of musculoskeletal system diseases, as well as the clinical research advancements of UHF-MR in musculoskeletal diseases. The aim is to enhance physicians' understanding of UHF-MR, broaden researchers' perspectives, further promote the development of novel contrast agents, the application of multimodal imaging techniques, and the integration of artificial intelligence-assisted diagnosis, thereby facilitating the clinical translation and application of UHF-MR in musculoskeletal system diseases.