Application status of tumor regression grading method after neoadjuvant chemoradiotherapy based on magnetic resonance imaging for locally advanced rectal cancer
As the incidence and mortality rates of colorectal cancer continue to rise globally,the treatment strategies for locally advanced rectal cancer (LARC) have garnered widespread attention. Currently,total mesorectal excision (TME) following neoadjuvant chemoradiotherapy (NCRT) is recommended as the standard treatment protocol for LARC. Although NCRT can significantly improve outcomes,there is notable variability in LARC patient responses to this treatment. Therefore,accurately assessing the efficacy of NCRT is crucial for clinical decision-making and personalized medicine. Current methods for assessing treatment efficacy include serum tumor markers,endoscopy,endorectal ultrasound,and CT/MRI,each with its limitations. In recent years,the magnetic resonance tumor regression grade (mrTRG) has gained attention and recommendation for its advantages of radiation-free,multi-directional imaging,high soft tissue resolution and dynamic continuous observation. Hence,this article aims to analyze the latest domestic and foreign research literature,and focus on the research value and current status of mrTRG after NCRT in LARC patients.