慢性疼痛患者下行疼痛调制系统的磁共振成像研究进展

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原文链接

国家科技期刊平台
NETL
NSTL
万方数据

中文摘要：慢性疼痛是一种复杂的体验,给患者和社会都带来了重大负担.在慢性疼痛的神经机制研究中,虽然研究者们常常关注疼痛的感知和控制相关脑区,但往往忽视了下行疼痛调制系统(descending pain modulation system,DPMS)相关脑区在慢性疼痛中结构及功能改变对疼痛感知的抑制和促进作用.本文就慢性疼痛患者DPMS的结构及功能改变的最新MRI研究进展予以综述,旨在探究DPMS的生理和病理机制,进一步深化对慢性疼痛的理解.

外文标题：Progress in magnetic resonance imaging studies of the descending pain modulation system in patients with chronic pain

外文摘要：Chronic pain is a complex experience that significantly burdens both patients and society. Research on the neural mechanisms of chronic pain typically focus on the areas related to the perception and control of pain. However,there is often less attention to the structural and functional changes in the brain regions associated with the descending pain modulation system. These areas play key roles in both inhibiting and facilitating pain perception. This article reviews the latest MRI research progress on the structural and functional changes in the descending pain modulation system in patients with chronic pain,aiming to explore the physiological and pathological mechanisms of DPMS and further deepen the understanding of chronic pain.

外文关键词：

chronic paindescending pain modulation systemstructural magnetic resonance imagingfunctional magnetic resonance imagingdiffusion magnetic resonance imagingmagnetic resonance imaging

作者：

周慧玲、雷婷、陈莉、杜勇

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作者单位：

川北医学院附属医院放射科,南充 637000

关键词：

慢性疼痛下行疼痛调制系统结构磁共振成像功能磁共振成像扩散磁共振成像磁共振成像

基金：

国家临床重点专科建设项目南充市校科技战略合作专项

项目编号：

[2023]8720SXZRKX0011

出版年：

2024

DOI：

10.12015/issn.1674-8034.2024.08.030

磁共振成像

中国医院协会首都医科大学附属北京天坛医院

磁共振成像

CSTPCD北大核心

影响因子：1.38

ISSN：1674-8034

年,卷(期)：2024.15(8)