Objective:To investigate the evaluation value of cardiovascular magnetic resonance feature tracking technology (CMR-FT) in patients with long-term over-drinkers,and analyze the influencing factors of left ventricular myocardial strain parameters in patients. Materials and Methods:A total of 39 long-term over-drinker were recruited (drinking group) and 20 healthy volunteers with no drinking history (control group) were examined cardiac magnetic resonance cine examination. The global left ventricular anisotropic strain parameters of two groups were calculated by CVI42 software,and the parameters of the two groups were statistically analyzed. Multiple linear regression equation was used to analyze the relationship between the degree of left ventricular strain damage and average daily alcohol consumption and drinking time in drinking group. ROC curve was constructed to calculate the overall left ventricular anisotropic strain in the differential diagnosis of the two groups. Results:The radial,circumferential and longitudinal strains of the whole left ventricular myocardium in the drinking group were 29.43% (19.60%,33.97%),−17.14% (−19.38%,−13.57%),−13.75% (−16.37%,−9.89%),respectively,which were lower than those in the control group. The peak strain rates of the left ventricular systolic and diastolic phases in the drinking group were also lower than those in the control group (P<0.05). Regression equation analysis showed that daily alcohol consumption and drinking time were the influencing factors of left ventricular strain,and daily alcohol consumption has a greater impact on strain than drinking time. The sensitivity of distinguishing the overall myocardial strain of the left ventricle in both groups is above 70%. Conclusions:CMR-FT technique can quantitatively evaluate left ventricular myocardial strain in over-drinkers. The average daily alcohol consumption and drinking time are important factors influencing the degree of left ventricular myocardial strain injury.
关键词
磁共振成像/过量饮酒者/特征追踪/心肌应变/影响因素
Key words
magnetic resonance/over-drinkers/feature tracking/myocardial strain/influencing factor