Feasibility study of 3D high-resolution compressed sensing contrast-enhanced whole-body MRA imaging technology
Objective:To investigate the feasibility and clinical value of 3D high-resolution compressed sensing contrast-enhanced whole-body magnetic resonance angiography(3D-CS-CE-MRA)with single injection and half-dose contrast agent.Materials and Methods:A total of 83 patients who were suspected of systemic arterial disease and underwent MRI systemic vascular examination were prospectively enrolled and randomly divided into two groups,A and B,with 44 patients in group A and 39 patients in group B.Group A underwent 3D-CS-CE-MRA scanning with a total contrast agent volume of 0.15 mmol/kg injected at a flow rate of 2 mL/s,while group B underwent conventional 3D high-resolution contrast-enhanced whole-body magnetic resonance angiography(3D-CE-MRA)scanning with a total contrast agent volume of 0.3 mmol/kg administered in two doses of 0.15 mmol/kg each at a flow rate of 2 mL/s.Two experienced radiologists independently scored the qualitative image quality of 25 arterial segments,and signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)were measured for the common carotid artery,abdominal aorta,femoral artery,and popliteal artery.The independent samples t-test and the Wilcoxon rank sum test was used for statistical analysis.Results:There was no significant difference in SNRs and CNRs for the common carotid artery,the femoral artery and the popliteal artery(all PP＞0.05),but there was significant difference in SNRs and CNRs for the abdominal aorta(all P＜0.05),the average value of group B was higher than that of group A.The average score of 3D-CS-CE-MRA was better than 3D-CE-MRA[(3.41±0.52)vs.(3.18±0.48),P＜0.05].There was no significant difference in scores of abdominal aorta,renal artery,superior mesenteric artery,celiac trunk,common iliac artery,external iliac artery,anterior tibial artery,and peroneal artery(all P＞0.05);there was no difference in image quality between group A and B.There was significant difference in scores of common carotid artery,brachiocephalic trunk,vertebral artery,thoracic aorta,femoral artery,popliteal artery,and posterior tibial artery(all P＜0.05),the scores of group A was higher than group B.Conclusions:Compared with conventional 3D-CE-MRA,3D-CS-CE-MRA can quickly complete magnetic resonance whole-body vascular examination with only one contrast agent injection and subtractionless,under the premise of ensuring image quality,it reduces the amount of contrast agent,shortens the examination time,and improves patient tolerance,and has great clinical application value.
magnetic resonance imagingcompressed sensingmulti-echo Dixoncontrast-enhancedwhole-body magnetic resonance angiography
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