Advances in behavior and imaging studies of cognitive flexibility changes in neurodegenerative disease
Cognitive flexibility refers to the individual to be able to quickly adapt to changing circumstances,and in the process to switch quickly thinking mode and the ability of adaptation in response.In neurodegenerative diseases such as Alzheimer's disease,Parkinson's disease and amyotrophic lateral sclerosis can be observed in the patients with flexibly shift their own mental processes and behavior to adapt the environment change ability dropped significantly(i.e,impaired cognitive flexibility).This article aims to review and summarize the previous research progress on behavioral assessment methods and imaging studies of cognitive flexibility in neurodegenerative diseases,so as to provide a theoretical basis for the diagnosis and treatment of cognitive flexibility decline caused by neurodegenerative diseases.
cognitive flexibilityneurodegenerative diseasesmagnetic resonance imagingAlzheimer's diseaseParkinson's diseaseWisconsin Card Sorting Test
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