重度抑郁症患者脑网络有效连接的磁共振成像研究进展
Magnetic resonance imaging research progress of effective brain network connectivity in patients with major depressive disorder
孙进楠 1伊伟 1黄俊霖 1任瑞2
作者信息
- 1. 滨州医学院医学影像学院,烟台 264003
- 2. 滨州医学院附属医院放射科,滨州 256603
- 折叠
摘要
重度抑郁症(major depressive disorder,MDD)是一种以持续悲伤为特征,以精力缺乏、情绪低落、睡眠异常、思维迟缓等为主要表现的精神障碍类疾病.有效连接(effective connectivity,EC)作为一种可以揭示脑区间因果关系的研究方法,在MDD的研究中起着重要作用.本文将对EC分析方法、EC在MDD不同脑网络和重要脑区节点中的研究及临床治疗后变化进行综述,旨在进一步揭示MDD的发病机制以及为治疗靶点的研究提供参考与技术支持.
Abstract
Major depressive disorder(MDD)is a kind of mental disorder characterized by persistent sadness,lack of energy,low mood,abnormal sleep,slow thinking and so on.As a research method that can reveal the causal relationship between brain regions,effective connection(EC)plays an important role in the study of MDD.This article reviews the EC analysis methods,the research of EC in different brain networks and important brain regions of MDD,and the changes of EC after clinical treatment,in order to further reveal the pathogenesis of MDD and provide reference and technical support for the research of therapeutic targets.
关键词
重度抑郁症/有效连接/磁共振成像/药物治疗/重复经颅刺激/电休克治疗/深部脑刺激Key words
major depressive disorder/effective connection/magnetic resonance imaging/drug therapy/repetitive transcranial magnetic stimulation/electroconvulsive therapy/deep brain stimulation引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据