伴中央颞区棘波的儿童良性癫痫(benign childhood epilepsy with centrotemporal spikes,BECTS)是儿童期最常见的局灶性癫痫之一,其病生机制、临床表现、治疗管理等是近来癫痫研究的热点方向.MRI中的三维T1加权成像、功能磁共振成像、弥散张量成像、脑电联合功能磁共振、多模态成像等序列可以分析患儿的脑结构和脑功能特征,对疾病研究有重要意义.本文回顾了 MRI在分析BECTS患者大脑发育及认知水平、指导患者病灶定位中的价值,并且鉴别了抗癫痫药物对大脑产生的影响以及判断患者的预后,旨在为未来进一步探索BECTS发病机制和指导临床管理提供参考.
MRI progress of benign childhood epilepsy with centrotemporal spikes
Benign childhood epilepsy with centrotemporal spikes(BECTS)is one of the most common focal epilepsy in childhood.MRI is of great significance to disease research,which can analyze the structure and functional characteristics of brains.It contains three dimensions T1-weighted imaging,functional MRI,diffusion-tensor imaging,simultaneous electroencephalogram and functional MRI,multimodal MRI and so on.This study aims to review the radiological technology used to analyze the brain development and cognitive levels of patients,guide lesion localization in BECTS,identify effects of antiepileptic drugs and estimate the prognosis of patients.It provides a reference for exploring the pathogenesis of BECTS and guiding clinical management in the future.
benign childhood epilepsy with centrotemporal spikesrolandic epilepsymagnetic resonance imagingstructural magnetic resonance imagingfunctional magnetic resonance imaging