Current status and challenges of MRI technology in the study of the glymphatic system in the human brain
The glymphatic system is a crucial system within the central nervous system responsible for clearing metabolic waste and maintaining fluid homeostasis,and it has recently become a hot topic in neuroscience research.Non-invasive MRI is a commonly used technique to assess the structure and function of the glymphatic system in the human brain.Specific MRI techniques include gadolinium-enhanced dynamic imaging,diffusion tensor imaging analysis,perivascular space imaging,choroid plexus volume analysis,arterial spin labeling,and blood oxygen level-dependent imaging.This article reviews the application and advancements of non-invasive MRI techniques in the study of the glymphatic system in the human brain,detailing their advantages and limitations to provide a reference for further clinical research.
glial lymphatic systemcentral nervous systemcerebrospinal fluidmagnetic resonance imagingdiffusion tensor imaging analysis along the perivascular spaceperivascular space
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